Continuous Chromatography of Peptides: Leading the Innovation in Peptide Manufacturing and Purification
Matteo Villian
Vice President CMC Development, Bachem
The current modus operandi for the downstream processing of synthetic peptides is reversed phase chromatography performed in batch mode. Continuous chromatography is expected to be a disruptive technology for this very cost intensive part of synthetic peptide manufacturing. Results from recent studies and thoughts regarding the control strategy will be discussed.
Matteo joined Bachem in 2004 as Director of Research. During his career at Bachem Americas he covered both the position of VP of R&D responsible for process development, and VP of Manufacturing responsible for commercial production. In his current position as VP of CMC Development, he supports Bachem customers in identifying the activities assuring a successful CMC development. Matteo holds a Doctorate in Chemistry and Pharmaceutical Technology from University of Milano, School of Pharmacy.