Ab initio Computational Peptide Discovery: Concepts and Examples.
Amit Michaeli
CTO, Pepticom Ltd.
The addition of computational peptide discovery to existing methodologies presents new opportunities for both academia and industry. In this talk I will introduce Pepticom’s computational discovery platform, cover the problem at hand and its solution complexity. This will be followed by a short summary of successful discovery stories including: A chaperone that rescues a misfolded protein; protein-protein interaction chaperones; and cyclic immunomodulators composed of both L and D amino acids. Finally, I will share Pepticom’s long term vision of an end-product integrated discovery platform.